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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NEK1
All Species:
9.7
Human Site:
T695
Identified Species:
17.78
UniProt:
Q96PY6
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96PY6
NP_036356.1
1258
142828
T695
S
L
T
D
T
R
E
T
S
E
E
M
Q
K
T
Chimpanzee
Pan troglodytes
XP_001153129
1258
142786
T695
S
L
T
D
T
R
E
T
S
E
E
M
Q
K
T
Rhesus Macaque
Macaca mulatta
XP_001082793
1258
142958
I695
S
L
T
D
I
R
E
I
S
E
E
M
Q
K
T
Dog
Lupus familis
XP_543184
1286
146207
T723
S
L
S
D
T
Q
E
T
S
E
D
M
Q
K
A
Cat
Felis silvestris
Mouse
Mus musculus
P51954
1203
136672
E649
S
L
T
D
T
Q
E
E
E
M
E
K
S
N
S
Rat
Rattus norvegicus
NP_001099552
648
74414
I124
K
H
V
H
D
R
K
I
L
H
R
D
I
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513277
864
98961
Q340
N
S
P
G
G
A
Q
Q
P
I
S
V
S
R
A
Chicken
Gallus gallus
XP_420401
1281
145243
V709
N
V
T
A
A
Q
E
V
K
E
E
I
K
K
P
Frog
Xenopus laevis
Q7ZZC8
944
104521
T420
V
S
C
G
S
D
F
T
V
C
I
T
D
E
G
Zebra Danio
Brachydanio rerio
Q90XC2
697
76523
E173
T
P
C
Y
I
S
P
E
L
C
E
G
K
P
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782796
1091
120115
I567
L
K
D
D
D
P
Q
I
S
A
E
E
R
R
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9CAU7
606
68016
G82
C
Y
V
C
I
I
I
G
Y
C
K
G
G
D
M
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
P48479
858
94329
I334
L
E
T
E
K
S
S
I
R
A
E
I
D
A
S
Conservation
Percent
Protein Identity:
100
99.6
97.5
85
N.A.
79.2
45.9
N.A.
30.2
66.2
22.4
22.7
N.A.
N.A.
N.A.
N.A.
32.9
Protein Similarity:
100
99.7
98.4
90.8
N.A.
85.6
48.5
N.A.
44.3
78
39.2
34.4
N.A.
N.A.
N.A.
N.A.
48.5
P-Site Identity:
100
100
86.6
73.3
N.A.
46.6
13.3
N.A.
0
33.3
6.6
6.6
N.A.
N.A.
N.A.
N.A.
20
P-Site Similarity:
100
100
86.6
93.3
N.A.
60
26.6
N.A.
26.6
66.6
20
20
N.A.
N.A.
N.A.
N.A.
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
21.9
N.A.
20.1
Protein Similarity:
N.A.
N.A.
N.A.
33.7
N.A.
35.1
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
6.6
N.A.
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
8
8
8
0
0
0
16
0
0
0
8
16
% A
% Cys:
8
0
16
8
0
0
0
0
0
24
0
0
0
0
0
% C
% Asp:
0
0
8
47
16
8
0
0
0
0
8
8
16
8
0
% D
% Glu:
0
8
0
8
0
0
47
16
8
39
62
8
0
8
0
% E
% Phe:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
16
8
0
0
8
0
0
0
16
8
0
8
% G
% His:
0
8
0
8
0
0
0
0
0
8
0
0
0
0
0
% H
% Ile:
0
0
0
0
24
8
8
31
0
8
8
16
8
0
0
% I
% Lys:
8
8
0
0
8
0
8
0
8
0
8
8
16
47
8
% K
% Leu:
16
39
0
0
0
0
0
0
16
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
8
0
31
0
0
8
% M
% Asn:
16
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% N
% Pro:
0
8
8
0
0
8
8
0
8
0
0
0
0
8
8
% P
% Gln:
0
0
0
0
0
24
16
8
0
0
0
0
31
0
0
% Q
% Arg:
0
0
0
0
0
31
0
0
8
0
8
0
8
16
0
% R
% Ser:
39
16
8
0
8
16
8
0
39
0
8
0
16
0
24
% S
% Thr:
8
0
47
0
31
0
0
31
0
0
0
8
0
0
24
% T
% Val:
8
8
16
0
0
0
0
8
8
0
0
8
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
8
0
0
0
0
8
0
0
0
0
0
8
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _